|
|
L-glutamate + L-cysteine + ATP <=> gamma-Glu-L-Cys + ADP + phosphate + H+
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
BMK
|
|
BRENDA:
BR112
KEGG:
R00894
MetaCyc:
GLUTCYSLIG-RXN
SABIO-RK:
1217
|
|
|
|
glycine + gamma-Glu-L-Cys + ATP <=> glutathione + ADP + phosphate + H+
|
6.3.2.3
glutathione synthase
|
–
|
BMK
|
|
BRENDA:
BR119
KEGG:
R00497
MetaCyc:
GLUTATHIONE-SYN-RXN
SABIO-RK:
927
|
|
|
|
gamma-Glu-L-Cys + NADP+ <=> H+ + bis-gamma-glutamylcystine + NADPH
|
1.8.1.13
bis-gamma-glutamylcystine reductase
|
–
|
BK
|
|
BRENDA:
BR36930
KEGG:
R02742
MetaCyc:
1.6.4.9-RXN
|
|
|
|
beta-Alanine + gamma-Glu-L-Cys + ATP <=> H+ + phosphate + gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP
|
6.3.2.23
homoglutathione synthase
6.3.2.3
glutathione synthase
|
–
–
|
M
|
|
BRENDA:
BR48380
KEGG:
R02741
MetaCyc:
HOMOGLUTATHIONE-SYNTHASE-RXN
|
|
|
|
hercynine + gamma-Glu-L-Cys + O2 <=> S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine_S-oxide + H2O
|
1.14.99.50
gamma-glutamyl hercynylcysteine S-oxide synthase
|
–
|
MK
|
|
BRENDA:
BR51393
KEGG:
R11013
MetaCyc:
RXN-14430
|
|
|
|
gamma-Glu-L-Cys <=> 5-oxoproline + L-cysteine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
K
|
|
BRENDA:
BS321706
KEGG:
R02743
|
|
|
|
glutathione + H2O <=> gamma-Glu-L-Cys + glycine
|
3.4.17.b
|
–
|
|
|
MetaCyc:
RXN-19585
|
|
|
|
GTP + L-glutamate + L-cysteine <=> GDP + phosphate + gamma-Glu-L-Cys
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS505
|
|
|
|
GTP + gamma-Glu-L-Cys + glycine <=> GDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS560
|
|
|
|
UTP + L-glutamate + L-cysteine <=> UDP + phosphate + gamma-Glu-L-Cys
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS506
|
|
|
|
CTP + gamma-Glu-L-Cys + glycine <=> CDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS559
|
|
|
|
UTP + gamma-Glu-L-Cys + glycine <=> UDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS558
|
|
|
|
dATP + gamma-Glu-L-Cys + glycine <=> dADP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS557
|
|
|
|
ITP + gamma-Glu-L-Cys + glycine <=> IDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS561
|
|
|
|
gamma-Glu-L-Cys + Gly-Gly <=> L-cysteine + 5-L-glutamyl-Gly-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS388714
|
|
|
|
ATP + gamma-Glu-L-Cys + L-alanine <=> ADP + phosphate + gamma-Glu-Cys-Ala
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379341
|
|
|
|
ATP + gamma-Glu-L-Cys + N-hydroxyglycine <=> ADP + phosphate + gamma-Glu-Cys-N-hydroxyglycine
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS565
|
|
|
|
ATP + gamma-Glu-L-Cys + L-serine <=> ADP + phosphate + gamma-Glu-Cys-Ser
|
6.3.2.23
homoglutathione synthase
6.3.2.3
glutathione synthase
|
–
–
|
|
|
BRENDA:
BS427379
|
|
|
|
ATP + gamma-Glu-L-Cys + 4-aminobutanoate <=> ADP + phosphate + gamma-glutamylcysteinyl-4-aminobutyrate
|
6.3.2.23
homoglutathione synthase
6.3.2.3
glutathione synthase
|
–
–
|
|
|
BRENDA:
BS363613
|
|
|
|
ATP + gamma-Glu-L-Cys + glycine <=> ADP + phosphate + gamma-glutamylcysteinylglycine
|
6.3.2.23
homoglutathione synthase
|
–
|
|
|
BRENDA:
BS363612
|
|
|
|
ATP + gamma-Glu-L-Cys + Aminooxyacetate <=> ADP + phosphate + gamma-Glu-Cys-aminoxyacetate
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS564
|
|
|
|
ATP + gamma-Glu-L-Cys + aminomethanesulfonic_acid <=> ADP + phosphate + gamma-Glu-L-Cys-aminomethanesulfonic_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS566
|
|
|
|
ATP + gamma-Glu-L-Cys + 3-Amino-1-propanol <=> ADP + phosphate + L-gamma-glutamyl-N-(3-hydroxypropyl)-L-cysteinamide
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379327
|
|
|
|
ATP + gamma-Glu-L-Cys + 2-aminobutanoate <=> ADP + phosphate + gamma-Glu-L-Cys-alpha-aminobutyric_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379328
|
|
|
|
ATP + gamma-Glu-L-Cys + 3-aminoisobutanoate <=> ADP + phosphate + gamma-Glu-L-Cys-beta-aminoisobutyric_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379331
|
|
|
|
ATP + gamma-Glu-L-Cys + 3-aminoisobutanoate <=> ADP + phosphate + gamma-L-Glu-L-Cys-beta-aminoisobutyric_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379332
|
|
|
|
ATP + gamma-Glu-L-Cys + D-alanine <=> ADP + phosphate + gamma-Glu-L-Cys-D-Ala
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379333
|
|
|
|
ATP + gamma-Glu-L-Cys + D-serine <=> ADP + phosphate + gamma-Glu-L-Cys-D-Ser
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379334
|
|
|
|
ATP + gamma-Glu-L-Cys + ethanolamine <=> ADP + phosphate + gamma-Glu-L-Cys-ethanolamine
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379335
|
|
|
|
ATP + gamma-Glu-L-Cys + 4-aminobutanoate <=> ADP + phosphate + gamma-L-Glu-L-Cys-gamma-aminobutyric_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379337
|
|
|
|
ATP + gamma-Glu-L-Cys + L-2,3-diaminopropionic_acid <=> ADP + phosphate + gamma-Glu-L-Cys-L-2,3-diaminopropionic_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379338
|
|
|
|
ATP + gamma-Glu-L-Cys + L-2,3-diaminopropionic_acid <=> ADP + phosphate + gamma-L-Glu-L-Cys-L-2,3-diaminopropionic_acid
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379339
|
|
|
|
ATP + gamma-Glu-L-Cys + L-alanine <=> ADP + phosphate + gamma-Glu-L-Cys-L-Ala
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379340
|
|
|
|
ATP + gamma-Glu-L-Cys + L-ornithine <=> ADP + phosphate + gamma-Glu-L-Cys-L-Orn
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379342
|
|
|
|
5-L-glutamyl-4-nitroanilide + L-cysteine <=> 4-nitroaniline + gamma-Glu-L-Cys
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321642
|
|